Piglet pre-weaning mortality is a significant challenge that directly impacts the productivity and profitability of swine herds. Understanding the non-infectious factors contributing to PWM is essential for enhancing animal welfare, minimizing production losses and ultimately improving farm profitability. This KelAcademy article delves into the critical elements influencing PWM, such as piglet birth weight, colostrum intake, and sow management. Additionally, it offers practical strategies that farmers can implement to reduce piglet mortality and improve overall herd performance.